BIOCH 465 - Methods in Molecular Biophysics

★ 3 (fi 6) (either term, 3-0-0) Survey of biophysical methods used in the characterization and structural determination of biological macromolecules, from ensemble measurements to single-molecule detection. Topics include mass spectrometry, optical spectroscopy, light microscopy, X-ray and neutron diffraction, electron microscopy, molecular dynamics and nuclear magnetic resonance. Emphasis is on using techniques in evaluating structure-function relationships through the discussion of representative macromolecular systems. Prerequisites: BIOCH 320 with a minimum grade of B- or consent of the Department. This course cannot be taken for credit if credit has already been obtained in BIOCH 460.